SELECT *
FROM s_ticklist_ETR
WHERE zeit > '2004-04-08-12:22:06'
ORDER BY zeit
LIMIT 0 , 1

0.2560 sek

EXPLAIN

table           type    possible_keys   key   key_len  ref   rows    Extra
s_ticklist_ETR  range   NULL            NULL  NULL     NULL  160774  Using where; Using filesort